An overview of piperazine scaffold as promising nucleus for different therapeutic targets - Sharma, A.; Wakode, S.; Fayaz, F.; Khasimbi, S.; Pottoo, F. H.; Kaur, A. (Curr Pharm Des, 2020)

Piperazine: an excellent catalyst for the synthesis of 2-amino-3-cyano-4H-pyrans derivatives in aqueous medium - Yousefi, M. R.; Goli-Jolodar, O.; Shirini, F. (Bioorg Chem, 2018)

7-[(4-Substituted)) piperazine-1-yl] derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents - Azema, J.; Guidetti, B.; Dewelle, J.; Calve, B. L.; Mijatovic, T.; Korolyov, A.; Vaysse, J.; Malet-Martino, M.; Martino, R.; Kiss, R. (Bioorg Med Chem, 2009)

Synthesis and antidepressant activity of a series of arylalkanol and aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7 - Gu, Z. S.; Xiao, Y.; Zhang, Q. W.; Li, J. Q. (Bioorg Med Chem Lett, 2017)

Tert-butyl4-[(1-phenyl-1H-pyrazol-4-yl) methyl] piperazine-1-carboxylate (LQFM104)-new piperazine derivative with antianxiety and antidepressant-like effects: putative role of serotonergic system - Silva, D. M.; Sanz, G.; Vaz, B. G.; Carvalho, F. S.; Liao, L. M.; Oliveira, D. R.; Moreira, L. K. S.; Cardoso, C. S.; Brito, A. F.; Silva, D. P. B.; Rocha, F. F.; Santana, L. G. C.; et al. (Biomed Pharmacother, 2018)

Inhibition of noroviruses by piperazine derivatives - Dou, D.; He, G.; Mandadapu, S. R.; Aravapalli, S.; Kim, Y.; Chang, K. O.; Groutas, W. C. (Bioorg Med Chem Lett, 2012)

In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase - Bassetto, M.; Leyssen, P.; Neyts, J.; Yerukhimovich, M. M.; Frick, D. N.; Courtney-Smith, M.; Brancale, A. (Eur J Med Chem, 2017)

Piperazine: a promising scaffold with analgesic and anti-inflammatory potential - Jain, A.; Chaudhary, J.; Khaira, H.; Chopra, B.; Dhingra, A. (Drug Res, 2021)

Design, synthesis, evaluation, and molecular docking of ursolic acid derivatives containing a nitrogen heterocycle as anti-inflammatory agents - Wei, Z. Y.; Chi, K. Q.; Wang, K. S.; Wu, J.; Liu, L. P.; Piao, H. R. (Bioorg Med Chem Lett, 2018)

An- inflammatory effect of a new piperazine derivative: (4-methylpiperazin-1-yl) (1-phenyl-1H-pyrazol-4-yl) methanone - Batista, D. C.; Silva, D. P. B.; Florentino, I. F.; Cardoso, C. S.; Goncalves, M. P.; Valadares, M. C.; Sanz, G.; Vaz, B. G.; Costa, E. A.; Menegatti, R. (Inflammopharmacology, 2018)

Synthesis of novel benzodioxane midst piperazine moiety decorated chitosan silver nanoparticle against biohazard pathogens and as potential anti-inflammatory candidate: a molecular docking studies - Karthik, C. S.; Manukumar, H. M.; Ananda, A. P.; Nagashree, S.; Rakesh, K. P.; Mallesha, L.; Qin, H. L.; Umesha, S.; Mallu, P.; Krishnamurthy, N. B. (Int J Biol Macromol, 2018)

Preparation and in vitro antioxidant activity of some novel flavone analogues bearing piperazine moiety - Berczynski, P.; Kladna, A.; Dundar, O. B.; Murat, H. N.; Sari, E.; Kruk, I.; Aboul-Enein, H. Y. (Bioorg Chem, 2020)

Chrysin-piperazine conjugates as antioxidant and anticancer agents - Patel, R. V.; Mistry, B.; Syed, R.; Rathi, A. K.; Lee, Y. J.; Sung, J. S.; Shinf, H. S.; Keum, Y. S. (Eur J Pharm Sci, 2016)

Piperazine derivatives with central pharmacological activity used as therapeutic tools - Brito, A. F.; Moreira, L. K. S.; Menegatti, R.; Costa, E. A. (Fundam Clin Pharmacol, 2018)

Piperazine derivatives as iron chelators: a potential application in neurobiology - Abdelsayed, S.; Ha Duong, N. T.; Bureau, C.; Michel, P. P.; Hirsch, E. C.; Hage Chahine, J. M.; Serradji, N. (Biometals, 2015)

2-benzoylbenzofuran derivatives possessing piperazine liker as anticancer agents - Gao, H.; Zhang, X.; Pu, X. J.; Zheng, X.; Liu, B.; Rao, G. X.; Wan, C. P.; Mao, Z. W. (Bioorg Med Chem Lett, 2019)

Synthesis and anticancer activity evaluation of some benzothiazole-piperazine derivatives - Gurdal, E. E.; Buclulgan, E.; Durmaz, I.; Cetin-Atalay, R.; Yarim, M. (Anticancer Agents Med Chem, 2015)

Piperazine derivatives for therapeutic use: a patent review (2010-present) - Rathi, A. K.; Syed, R.; Shin, H. S.; Patel, R. V. (Expert Opin Ther Pat, 2016)

Apoptosis: a review of programmed cell death - Elmore, S. (Toxicol Pathol, 2007)

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy - Fulda, S.; Debatin, K. M. (Oncogene, 2006)

Cytotoxic effects of polymethoxyflavones isolated from Kaempferiaparviflora - Alamgir Hossain, M. D.; Wongsrikaew, N.; Yoo, G. W.; Han, J. H.; Shin, C. G. (J Korean Soc Appl Biol Chem, 2012)

Influence of pretreatment with immunosuppressive drugs on viral proliferation - Lee, G. E.; Shin, C. G. (J Microbiol Biotechnol, 2018)

Apoptosis induced by enniatins H and MK 1688 isolated from Fusariumoxysporum FB1501 - Hyun, U.; Lee, D. H.; Lee, C.; Shin, C. G. (Toxicon, 2009)

The basics of western blotting - Jensen, E. C. (Anat Rec, 2012)

Lactate dehydrogenase assay for assessment of polycation cytotoxicity - Parhamifar, L.; Andersen, H.; Moghimi, S. M. (Methods Mol Biol, 2019)

Pharmacology of camptothecin esters - Liehr, J. G.; Harris, N. J.; Mendoza, J.; Ahmed, A. E.; Giovanella, B. C. (Ann NY Acad Sci, 2006)

Beyond apoptosis: caspase regulatory mechanisms and functions in vivo - Kuranaga, E. (Genes Cells, 2012)

Radiosensitization of solid tumors by z-vad, a pan-caspase inhibitor - Moretti, L.; Kim, K. W.; Jung, D. K.; Willey, C. D.; Lu, B. (Mol Cancer Ther, 2009)

Molecular medhanisms of apoptosis and roles in cancer development and treatment - Golder, S.; Khaniani, M. S.; Derakhshan, S. M.; Baradaran, B. (Asian Pac J Cancer Prev, 2015)

Principles of current cancer chemotherapy - Wiemann, M. C.; Calabresi, P. (Compr Ther, 1983)

The anti-cancer effect of quercetin: molecular implications in cancer metabolism - Reyes-Farias, M.; Carrasco-Pozo, C. (Int J Mol Sci, 2019)

Piperazine as an inexpensive and efficient ligand for pd-catalyzed homocoupling reactions to synthesize bipyridines and their analogues - Chen, M.; Hu, J.; Tang, X.; Zhu, Q. (Curr Org Synth, 2019)