Impact of obstructive sleep apnea and current treatments on the development and progression of type 2 diabetes - Faria, A.; Laher, I.; Fasipe, B.; Ayas, N. T. (Curr Diabetes Rev, 2022)

Topical aspirin administration improves cutaneous Wound Healing in Diabetic mice through a phenotypic switch of Wound macrophages toward an anti-inflammatory and Proresolutive Profile characterized by LXA4 release - Dardenne, C.; Salon, M.; Authier, H.; Meunier, E.; AlaEddine, M.; Bernad, J.; Bouschbacher, M.; Lefevre, L.; Pipy, B.; Coste, A. (Diabetes, 2022)

Management of a Diabetic Foot - Hart, T.; Milner, R.; Cifu, A. (JAMA, 2017)

Ridiandries A, Tan J, Bursill CA. The role of chemokines in Wound Healing. INT J MOL SCI 2018;19.

Wound healing and its impairment in the diabetic foot - Falanga, V. (Lancet, 2005)

A small molecule HIF-1alpha stabilizer that accelerates diabetic wound healing - Li, G.; Ko, C. N.; Li, D.; Yang, C.; Wang, W.; Yang, G. J.; Primo, C.; Wong, V.; Xiang, Y.; Lin, L.; Ma, D. L.; Leung, C. H. (NAT COMMUN, 2021)

Fang WC, Lan CE. The epidermal keratinocyte as a therapeutic target for management of Diabetic wounds. INT J MOL SCI 2023;24.

Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing - Chen, S.; Zhu, Y.; Xu, Q.; Jiang, Q.; Chen, D.; Chen, T.; Xu, X.; Jin, Z.; He, Q. (NAT COMMUN, 2022)

Khalid M, Petroianu G, Adem A. Advanced Glycation End products and Diabetes Mellitus: mechanisms and perspectives. Biomolecules 2022;12.

Advanced Glycation End products in the skin: Molecular mechanisms, methods of Measurement, and Inhibitory pathways - Chen, C. Y.; Zhang, J. Q.; Li, L.; Guo, M. M.; He, Y. F.; Dong, Y. M.; Meng, H.; Yi, F. (Front Med (Lausanne), 2022)

Role of keratinocytes in healing of chronic wounds - Pastar, I.; Stojadinovic, O.; Tomic-Canic, M. (Surg Technol Int, 2008)

Keratinocyte function in Normal and Diabetic wounds and Modulation by FOXO1 - Wang, Y.; Graves, D. T. (J DIABETES RES, 2020)

Advanced glycation end products (AGEs) promote melanogenesis through receptor for AGEs - Lee, E. J.; Kim, J. Y.; Oh, S. H. (Sci Rep, 2016)

FOXO1 differentially regulates both normal and diabetic wound healing - Zhang, C.; Ponugoti, B.; Tian, C.; Xu, F.; Tarapore, R.; Batres, A.; Alsadun, S.; Lim, J.; Dong, G.; Graves, D. T. (J CELL BIOL, 2015)

Pioglitazone inhibits advanced glycation end product-induced TNF-alpha and MMP-13 expression via the antagonism of NF-kappaB activation in chondrocytes - Chen, C.; Ma, C.; Zhang, Y.; Zeng, Y.; Li, Y.; Wang, W. (Pharmacology, 2014)

Matrix metalloproteinase 9 induces keratinocyte apoptosis through FasL/Fas pathway in diabetic wound - Liang, Y.; Yang, C.; Lin, Y.; Parviz, Y.; Sun, K.; Wang, W.; Ren, M.; Yan, L. (Apoptosis, 2019)

Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair - Wetzler, C.; Kampfer, H.; Stallmeyer, B.; Pfeilschifter, J.; Frank, S. (J INVEST DERMATOL, 2000)

The role of keratinocyte function on the defected diabetic wound healing - Hosseini, M. N. (Int J Burns Trauma, 2021)

D-mannose induces regulatory T cells and suppresses immunopathology - Zhang, D.; Chia, C.; Jiao, X.; Jin, W.; Kasagi, S.; Wu, R.; Konkel, J. E.; Nakatsukasa, H.; Zanvit, P.; Goldberg, N.; Chen, Q.; Sun, L.; et al. (NAT MED, 2017)

Mannose treatment: a Promising Novel Strategy to suppress inflammation - Zhang, W.; Cheng, H.; Gui, Y.; Zhan, Q.; Li, S.; Qiao, W.; Tong, A. (FRONT IMMUNOL, 2021)

D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial - Kranjcec, B.; Papes, D.; Altarac, S. (WORLD J UROL, 2014)

Carbohydrate-deficient glycoprotein syndrome type ib. Phosphomannose isomerase deficiency and mannose therapy - Niehues, R.; Hasilik, M.; Alton, G.; Korner, C.; Schiebe-Sukumar, M.; Koch, H. G.; Zimmer, K. P.; Wu, R.; Harms, E.; Reiter, K.; Figura, K.; Freeze, H. H.; et al. (J CLIN INVEST, 1998)

D-Mannose regulates hepatocyte lipid metabolism via PI3K/Akt/mTOR signaling pathway and ameliorates hepatic steatosis in alcoholic liver disease - Hu, M.; Chen, Y.; Deng, F.; Chang, B.; Luo, J.; Dong, L.; Lu, X.; Zhang, Y.; Chen, Z.; Zhou, J. (FRONT IMMUNOL, 2022)

Mannose ameliorates experimental colitis by protecting intestinal barrier integrity - Dong, L.; Xie, J.; Wang, Y.; Jiang, H.; Chen, K.; Li, D.; Wang, J.; Liu, Y.; He, J.; Zhou, J.; Zhang, L.; Lu, X.; et al. (NAT COMMUN, 2022)

D-Mannose ameliorates DNCB-induced atopic dermatitis in mice and TNF-alpha-induced inflammation in human keratinocytes via mTOR/NF-kappaB pathway - Luo, J.; Li, Y.; Zhai, Y.; Liu, Y.; Zeng, J.; Wang, D.; Li, L.; Zhu, Z.; Chang, B.; Deng, F.; Zhang, J.; Zhou, J.; et al. (INT IMMUNOPHARMACOL, 2022)

Puerarin improves diabetic wound healing via regulation of macrophage M2 polarization phenotype - Li, S.; Yang, P.; Ding, X.; Zhang, H.; Ding, Y.; Tan, Q. (Burns Trauma, 2022)

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling - Palsamy, P.; Subramanian, S. (Biochim Biophys Acta, 2011)

Mannan-binding lectin via Interaction with Cell Surface Calreticulin promotes senescence of activated hepatic stellate cells to Limit Liver Fibrosis Progression - Luo, J.; Li, L.; Chang, B.; Zhu, Z.; Deng, F.; Hu, M.; Yu, Y.; Lu, X.; Chen, Z.; Zuo, D.; Zhou, J. (Cell Mol Gastroenterol Hepatol, 2022)

Standardized protocols for differentiation of THP-1 cells to macrophages with distinct M(IFNgamma + LPS), M(IL-4) and M(IL-10) phenotypes - Baxter, E. W.; Graham, A. E.; Re, N. A.; Carr, I. M.; Robinson, J. I.; Mackie, S. L.; Morgan, A. W. (J IMMUNOL METHODS, 2020)

Mannose impairs tumour growth and enhances chemotherapy - Gonzalez, P. S.; O’Prey, J.; Cardaci, S.; Barthet, V.; Sakamaki, J. I.; Beaumatin, F.; Roseweir, A.; Gay, D. M.; Mackay, G.; Malviya, G.; Kania, E.; Ritchie, S.; et al. (Nature, 2018)

c-Myc upregulated by high glucose inhibits HaCaT differentiation by S100A6 transcriptional activation - Zhang, J.; Yang, P.; Liu, D.; Gao, M.; Wang, J.; Wang, X.; Liu, Y.; Zhang, X. (Front Endocrinol (Lausanne), 2021)

High-glucose environment disturbs the physiologic functions of keratinocytes: focusing on diabetic wound healing - Hu, S. C.; Lan, C. E. (J DERMATOL SCI, 2016)

Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P - Ai, Y. L.; Wang, W. J.; Liu, F. J.; Fang, W.; Chen, H. Z.; Wu, L. Z.; Hong, X.; Zhu, Y.; Zhang, C. X.; Liu, L. Y.; Hong, W. B.; Zhou, B.; et al. (CELL RES, 2023)

Zhang R, Yang Y, Dong W, Lin M, He J, Zhang X, Tian T, Yang Y, Chen K, Lei QY, Zhang S, Xu Y, Lv L. D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1. Proc Natl Acad Sci U S A 2022;119.

Notoginsenoside R1 protects against high glucose-Induced Cell Injury through AMPK/Nrf2 and downstream HO-1 signaling - Du, F.; Huang, H.; Cao, Y.; Ran, Y.; Wu, Q.; Chen, B. (Front Cell Dev Biol, 2021)

Xiao F, Rui S, Zhang X, Ma Y, Wu X, Hao W, Huang G, Armstrong DG, Chen Q, Deng W. Accelerating diabetic wound healing with Ramulus Mori (Sangzhi) alkaloids via NRF2/HO-1/eNOS pathway. PHYTOMEDICINE. 2024;134:155990.

Advanced glycation end products impair coronary artery BK channels via AMPK/Akt/FBXO32 signaling pathway - Li, X. Y.; Qian, L. L.; Wu, Y.; Zhang, Y. M.; Dang, S. P.; Liu, X. Y.; Tang, X.; Lu, C. Y.; Wang, R. X. (Diab Vasc Dis Res, 2023)

D-Mannose suppresses gammadelta T cells and alleviates murine psoriasis - Li, M.; Cheng, H.; Tian, D.; Yang, L.; Du, X.; Pan, Y.; Zhang, D.; Mei, X. (FRONT IMMUNOL, 2022)

d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1alpha/CCL20 in mice - Jiang, Q.; Wei, B.; You, M.; Zhou, X. (INT IMMUNOPHARMACOL, 2023)

Advanced glycation endproducts–role in pathology of diabetic complications - Ahmed, N. (Diabetes Res Clin Pract, 2005)

Advanced glycoxidation products and impaired diabetic wound healing - Peppa, M.; Stavroulakis, P.; Raptis, S. A. (WOUND REPAIR REGEN, 2009)

PMI-controlled mannose metabolism and glycosylation determines tissue tolerance and virus fitness - Liang, R.; Ye, Z. W.; Qin, Z.; Xie, Y.; Yang, X.; Sun, H.; Du, Q.; Luo, P.; Tang, K.; Hu, B.; Cao, J.; Wong, X. H.; et al. (NAT COMMUN, 2024)

Mannose is an insulin-regulated metabolite reflecting whole-body insulin sensitivity in man - Ferrannini, E.; Bokarewa, M.; Brembeck, P.; Baboota, R.; Hedjazifar, S.; Andersson, K.; Baldi, S.; Campi, B.; Muscelli, E.; Saba, A.; Sterner, I.; Wasen, C.; et al. (METABOLISM, 2020)

Autophagy activators stimulate the removal of advanced glycation end products in human keratinocytes - Laughlin, T.; Tan, Y.; Jarrold, B.; Chen, J.; Li, L.; Fang, B.; Zhao, W.; Tamura, M.; Matsubara, A.; Deng, G.; Wang, X.; Hakozaki, T. (J Eur Acad Dermatol Venereol, 2020)

Input/output cytokines in epidermal keratinocytes and the involvement in inflammatory skin diseases - Morizane, S.; Mukai, T.; Sunagawa, K.; Tachibana, K.; Kawakami, Y.; Ouchida, M. (FRONT IMMUNOL, 2023)

AMPK signaling in diabetes mellitus, insulin resistance and diabetic complications: a pre-clinical and clinical investigation - Entezari, M.; Hashemi, D.; Taheriazam, A.; Zabolian, A.; Mohammadi, S.; Fakhri, F.; Hashemi, M.; Hushmandi, K.; Ashrafizadeh, M.; Zarrabi, A.; Ertas, Y. N.; Mirzaei, S.; et al. (BIOMED PHARMACOTHER, 2022)

San Huang Xiao Yan recipe modulates the HMGB1-mediated abnormal inflammatory microenvironment and ameliorates diabetic foot by activating the AMPK/Nrf2 signalling pathway - Zhang, Z.; Zheng, Y.; Chen, N.; Xu, C.; Deng, J.; Feng, X.; Liu, W.; Ma, C.; Chen, J.; Cai, T.; Xu, Y.; Wang, S.; et al. (Phytomedicine, 2023)

Dapagliflozin alleviates advanced glycation end product induced podocyte injury through AMPK/mTOR mediated autophagy pathway - Yang, L.; Liang, B.; Li, J.; Zhang, X.; Chen, H.; Sun, J.; Zhang, Z. (CELL SIGNAL, 2022)

Akt1 controls insulin-driven VEGF biosynthesis from keratinocytes: implications for normal and diabetes-impaired skin repair in mice - Goren, I.; Muller, E.; Schiefelbein, D.; Gutwein, P.; Seitz, O.; Pfeilschifter, J.; Frank, S. (J INVEST DERMATOL, 2009)

Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse - Werner, S.; Breeden, M.; Hubner, G.; Greenhalgh, D. G.; Longaker, M. T. (J INVEST DERMATOL, 1994)